Help with API

Can someone give me an example query... of how I would supply the danbooru API with an MD5sum and have it supply me the associated metadata such as the tags?

Does it even support this?

Sorry if I'm kind of new to this sort of thing.

Use a tag search, something like this:

danbooru.donmai.us/post/index.xml?tags=status:any+md5:e455d2ac83382b4e2e5b1c01f5e20ac9

Doesn't include the notes/comments/pools.
You can search for several md5s at once, just separate them with commas.

Read the cheat sheet for some other ideas.