3rd panel on right: I have seen that head posture somewhere else...

wait.. how do i read this? should i read the left 4koma then right 4koma or left to right panel??

Its a two-colum 4koma. Always read right to left and top to bottom per column, unless otherwise stated. This 4koma is in Chinese, but I don't think there's a difference in direction of reading.

This appears to read left to right,but in 4-koma up-down strips.

It makes more sense that wa, but I've no clue why they did it like that.

Sanae is a good girl, its obviously her gods the one that make her do/say such horribly things

Mr.Obake said:
3rd panel on right: I have seen that head posture somewhere else...

It is indeed very familiar...